Occurrence of the new tetracycline resistance gene tet(W) in bacteria from the human gut.

نویسندگان

  • K P Scott
  • C M Melville
  • T M Barbosa
  • H J Flint
چکیده

Members of our group recently identified a new tetracycline resistance gene, tet(W), in three genera of rumen obligate anaerobes. Here, we show that tet(W) is also present in bacteria isolated from human feces. The tet(W) genes found in human Fusobacterium prausnitzii and Bifidobacterium longum isolates were more than 99.9% identical to those from a rumen isolate of Butyrivibrio fibrisolvens.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Detection of tetracycline resistance genes in bacteria isolated from fish farms using polymerase chain reaction

Five common tetracycline resistance genes tet(A), tet(B), tet(M), tet(O) and tet(S) were studied by polymerase chain reaction in 100 bacteria isolated from Iranian fish farms. In the antibiogram test most of the bacteria were either intermediately or completely resistant to tetracycline. Nine isolates out of 46 Aeromonas spp. contained eithe...

متن کامل

Survey and identification of Resistance Genes of Sulfanamide (sul2, sul3) and Tetracycline Tet (A), tet (C), tet (D) and intI Integron Genes in Escherichia Coli Isolated from Mastitis Samples

Background and Aims: Escherichia coli is a natural microflora of the human heart and all the warm animals. Mastitis is a disease caused by various pathogens. One of the important factors in the production of mastitis in the livestock is E. coli and is known as peripheral mastitis. The aim of this study was to isolate sulfonamide, integron and tetracycline resistance genes in E.coli isolated fro...

متن کامل

Comparative analysis of sequences flanking tet(W) resistance genes in multiple species of gut bacteria.

tet(W) is one of the most abundant tetracycline resistance genes found in bacteria from the mammalian gut and was first identified in the rumen anaerobe Butyrivibrio fibrisolvens 1.230, where it is highly mobile and its transfer is associated with the transposable chromosomal element TnB1230. In order to compare the genetic basis for tet(W) carriage in different bacteria, we studied sequences f...

متن کامل

Evaluation of resistance genes in Escherichia coli isolated from toilets in the Islamic Azad University, Mashhad and genome sequencing (tet B, tet A, tet R, OXA 10 and OXA 48) in tetracycline-resistant strains

Aims and Background: E. coli is a normal flora of the human and animal intestine that sometimes causes pathogenesis in the intestine and urinary tract. The aim of this study is to investigate resistance genes in E. coli isolated from toilets in the Islamic Azad University of Mashhad and perform genome sequencing in tetracycline-resistant strains. Methods: This cross-sectional study was perform...

متن کامل

The Gut as Reservoir of Antibiotic Resistance: Microbial Diversity of Tetracycline Resistance in Mother and Infant

The microbiota in the human gastrointestinal tract (GIT) is highly exposed to antibiotics, and may be an important reservoir of resistant strains and transferable resistance genes. Maternal GIT strains can be transmitted to the offspring, and resistances could be acquired from birth. This is a case study using a metagenomic approach to determine the diversity of microorganisms conferring tetrac...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 44 3  شماره 

صفحات  -

تاریخ انتشار 2000